Susan is a parody of the protagonist in Attack of the 50 Foot Woman (becoming exactly one inch shorter).
Susan is the second female protagonist in a DreamWorks Animation film, the first being Ginger from Chicken Run, the third being Eep from The Croods, the fourth being Poppy from Trolls, and the fifth being Yi from Abominable.
She is also the first female protagonist of an original DreamWorks Animation film and not to be one that is co-produced with Aardman.
In reality, a human who is 50 feet tall but is proportioned like a six-foot human would be unable to stand; because standing would entail 579 times the body mass being supported by bones and muscles of only 69 times the cross-section, and hence strength.
Susan has the biggest butt in the entire franchise.
Susan’s hair was brown in the beginning of the film but turned white when she became Ginormica. It is similar to Mei Lee the main protagonist of Disney/Pixar’s film Turning Red to when Mei Lee’s hair was black in the beginning of the film but turned red after her Red Panda curse.
